Disruption of Bcl-2 and Bcl-xL by viral proteins as a possible cause of cancer

The Bcl proteins play a critical role in apoptosis, as mutations in family members interfere with normal programmed cell death. Such events can cause cell transformation, potentially leading to cancer. Recent discoveries indicate that some viral proteins interfere with Bcl proteins either directly o...

Full description

Bibliographic Details
Main Authors: Alibek, Kenneth, Irving, Stephanie, Sautbayeva, Zarina, Kakpenova, Ainur, Bekmurzayeva, Aliya, Baiken, Yeldar, Imangali, Nurgul, Shaimerdenova, Madina, Mektepbayeva, Damel, Balabiyev, Arnat, Chinybayeva, Aizada
Format: Online
Language:English
Published: BioMed Central 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333878/