Drug Resistance in Cortical and Hippocampal Slices from Resected Tissue of Epilepsy Patients: No Significant Impact of P-Glycoprotein and Multidrug Resistance-Associated Proteins

Drug Resistance in Cortical and Hippocampal Slices from Resected Tissue of Epilepsy Patients: No Significant Impact of P-Glycoprotein and Multidrug Resistance-Associated Proteins

Drug resistant patients undergoing epilepsy surgery have a good chance to become sensitive to anticonvulsant medication, suggesting that the resected brain tissue is responsible for drug resistance. Here, we address the question whether P-glycoprotein (Pgp) and multidrug resistance-associated protei...

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Bibliographic Details
Main Authors: Sandow, Nora, Kim, Simon, Raue, Claudia, Päsler, Dennis, Klaft, Zin-Juan, Antonio, Leandro Leite, Hollnagel, Jan Oliver, Kovacs, Richard, Kann, Oliver, Horn, Peter, Vajkoczy, Peter, Holtkamp, Martin, Meencke, Heinz-Joachim, Cavalheiro, Esper A., Pragst, Fritz, Gabriel, Siegrun, Lehmann, Thomas-Nicolas, Heinemann, Uwe
Format: Online
Language:English
Published: Frontiers Media S.A. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332373/

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