Platelet Surface-Associated Activation and Secretion-Mediated Inhibition of Coagulation Factor XII

Coagulation factor XII (fXII) is important for arterial thrombosis, but its physiological activation mechanisms are unclear. In this study, we elucidated the role of platelets and platelet-derived material in fXII activation. FXII activation was only observed upon potent platelet stimulation (with t...

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Bibliographic Details
Main Authors: Zakharova, Natalia V., Artemenko, Elena O., Podoplelova, Nadezhda A., Sveshnikova, Anastasia N., Demina, Irina A., Ataullakhanov, Fazly I., Panteleev, Mikhail A.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331558/