Understanding Epistatic Interactions between Genes Targeted by Non-coding Regulatory Elements in Complex Diseases

Genome-wide association studies have proven the highly polygenic architecture of complex diseases or traits; therefore, single-locus-based methods are usually unable to detect all involved loci, especially when individual loci exert small effects. Moreover, the majority of associated single-nucleoti...

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Bibliographic Details
Main Authors: Sung, Min Kyung, Bang, Hyoeun, Choi, Jung Kyoon
Format: Online
Language:English
Published: Korea Genome Organization 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330252/