Molecular Characteristics of Noroviruses Genogroup I and Genogroup II Detected in Patients With Acute Gastroenteritis

Noroviruses are the leading cause of epidemic gastroenteritis, including foodborne outbreak, in Korea. The prevalence of human noroviruses was studied in diarrheal stool samples of patients with acute gastroenteritis by conventional duplex reverse transcription (RT)-PCR. Diarrheal stool samples were...

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Main Authors:	Ham, Heejin, Oh, Seah, Seung, Hyunjung, Jo, Sukju
Format:	Online
Language:	English
Published:	The Korean Society for Laboratory Medicine 2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330176/

id	pubmed-4330176
recordtype	oai_dc
spelling	pubmed-43301762015-03-01 Molecular Characteristics of Noroviruses Genogroup I and Genogroup II Detected in Patients With Acute Gastroenteritis Ham, Heejin Oh, Seah Seung, Hyunjung Jo, Sukju Brief Communication Noroviruses are the leading cause of epidemic gastroenteritis, including foodborne outbreak, in Korea. The prevalence of human noroviruses was studied in diarrheal stool samples of patients with acute gastroenteritis by conventional duplex reverse transcription (RT)-PCR. Diarrheal stool samples were collected from 1,685 patients from the local hospitals in Seoul. The prevalence of the noroviruses was 22.8% (222/972 patients) in 2012 and 11.2% (80/713 patients) in 2013, with a total of 17.9% (302/1,685 patients). Genotyping was performed on 302 norovirus-positive stool samples to reveal 5.6% prevalence of genogroup I (GI) (17/302) and 94.4% prevalence of genogroup II (GII) (285/302). The patients with norovirus-associated acute gastroenteritis mostly showed prevalence of GII norovirus, especially GII.4 (64.6%; 195/302). The Korean Society for Laboratory Medicine 2015-03 2015-02-12 /pmc/articles/PMC4330176/ /pubmed/25729728 http://dx.doi.org/10.3343/alm.2015.35.2.242 Text en © The Korean Society for Laboratory Medicine. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Ham, Heejin Oh, Seah Seung, Hyunjung Jo, Sukju
spellingShingle	Ham, Heejin Oh, Seah Seung, Hyunjung Jo, Sukju Molecular Characteristics of Noroviruses Genogroup I and Genogroup II Detected in Patients With Acute Gastroenteritis
author_facet	Ham, Heejin Oh, Seah Seung, Hyunjung Jo, Sukju
author_sort	Ham, Heejin
title	Molecular Characteristics of Noroviruses Genogroup I and Genogroup II Detected in Patients With Acute Gastroenteritis
title_short	Molecular Characteristics of Noroviruses Genogroup I and Genogroup II Detected in Patients With Acute Gastroenteritis
title_full	Molecular Characteristics of Noroviruses Genogroup I and Genogroup II Detected in Patients With Acute Gastroenteritis
title_fullStr	Molecular Characteristics of Noroviruses Genogroup I and Genogroup II Detected in Patients With Acute Gastroenteritis
title_full_unstemmed	Molecular Characteristics of Noroviruses Genogroup I and Genogroup II Detected in Patients With Acute Gastroenteritis
title_sort	molecular characteristics of noroviruses genogroup i and genogroup ii detected in patients with acute gastroenteritis
description	Noroviruses are the leading cause of epidemic gastroenteritis, including foodborne outbreak, in Korea. The prevalence of human noroviruses was studied in diarrheal stool samples of patients with acute gastroenteritis by conventional duplex reverse transcription (RT)-PCR. Diarrheal stool samples were collected from 1,685 patients from the local hospitals in Seoul. The prevalence of the noroviruses was 22.8% (222/972 patients) in 2012 and 11.2% (80/713 patients) in 2013, with a total of 17.9% (302/1,685 patients). Genotyping was performed on 302 norovirus-positive stool samples to reveal 5.6% prevalence of genogroup I (GI) (17/302) and 94.4% prevalence of genogroup II (GII) (285/302). The patients with norovirus-associated acute gastroenteritis mostly showed prevalence of GII norovirus, especially GII.4 (64.6%; 195/302).
publisher	The Korean Society for Laboratory Medicine
publishDate	2015
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330176/
_version_	1613188930375516160

Molecular Characteristics of Noroviruses Genogroup I and Genogroup II Detected in Patients With Acute Gastroenteritis

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