Methionine restriction slows down senescence in human diploid fibroblasts

Methionine restriction slows down senescence in human diploid fibroblasts

Methionine restriction (MetR) extends lifespan in animal models including rodents. Using human diploid fibroblasts (HDF), we report here that MetR significantly extends their replicative lifespan, thereby postponing cellular senescence. MetR significantly decreased activity of mitochondrial complex...

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Bibliographic Details
Main Authors: Kozieł, Rafał, Ruckenstuhl, Christoph, Albertini, Eva, Neuhaus, Michael, Netzberger, Christine, Bust, Maria, Madeo, Frank, Wiesner, Rudolf J, Jansen-Dürr, Pidder
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326930/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326930/

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