Arrestins regulate cell spreading and motility via focal adhesion dynamics
Cells lacking both nonvisual arrestins show excessive spreading, defects in focal adhesion disassembly, and sensitivity to microtubules. This phenotype is rescued by wild-type arrestins but not mutants deficient in clathrin binding, suggesting that arrestins regulate focal adhesion disassembly by li...
Main Authors: | , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
The American Society for Cell Biology
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325834/ |