Arrestins regulate cell spreading and motility via focal adhesion dynamics

Cells lacking both nonvisual arrestins show excessive spreading, defects in focal adhesion disassembly, and sensitivity to microtubules. This phenotype is rescued by wild-type arrestins but not mutants deficient in clathrin binding, suggesting that arrestins regulate focal adhesion disassembly by li...

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Bibliographic Details
Main Authors: Cleghorn, Whitney M., Branch, Kevin M., Kook, Seunghyi, Arnette, Christopher, Bulus, Nada, Zent, Roy, Kaverina, Irina, Gurevich, Eugenia V., Weaver, Alissa M., Gurevich, Vsevolod V.
Format: Online
Language:English
Published: The American Society for Cell Biology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325834/