Targeted treatment for chronic lymphocytic leukemia: clinical potential of obinutuzumab
Introduction of targeted agents revolutionized the treatment of chronic lymphocytic leukemia (CLL) in the past decade. Addition of chimeric monoclonal anti-CD20 antibody rituximab to chemotherapy significantly improved efficacy including overall survival (OS) in untreated fit patients; humanized ant...
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Format: | Online |
Language: | English |
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Dove Medical Press
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325625/ |