Clinical Utility of Exercise Training in Heart Failure with Reduced and Preserved Ejection Fraction

Reduced exercise tolerance is an independent predictor of hospital readmission and mortality in patients with heart failure (HF). Exercise training for HF patients is well established as an adjunct therapy, and there is sufficient evidence to support the favorable role of exercise training programs...

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Main Authors:	Asrar Ul Haq, Muhammad, Goh, Cheng Yee, Levinger, Itamar, Wong, Chiew, Hare, David L
Format:	Online
Language:	English
Published:	Libertas Academica 2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324467/

id	pubmed-4324467
recordtype	oai_dc
spelling	pubmed-43244672015-02-19 Clinical Utility of Exercise Training in Heart Failure with Reduced and Preserved Ejection Fraction Asrar Ul Haq, Muhammad Goh, Cheng Yee Levinger, Itamar Wong, Chiew Hare, David L Review Reduced exercise tolerance is an independent predictor of hospital readmission and mortality in patients with heart failure (HF). Exercise training for HF patients is well established as an adjunct therapy, and there is sufficient evidence to support the favorable role of exercise training programs for HF patients over and above the optimal medical therapy. Some of the documented benefits include improved functional capacity, quality of life (QoL), fatigue, and dyspnea. Major trials to assess exercise training in HF have, however, focused on heart failure with reduced ejection fraction (HFREF). At least half of the patients presenting with HF have heart failure with preserved ejection fraction (HFPEF) and experience similar symptoms of exercise intolerance, dyspnea, and early fatigue, and similar mortality risk and rehospitalization rates. The role of exercise training in the management of HFPEF remains less clear. This article provides a brief overview of pathophysiology of reduced exercise tolerance in HFREF and heart failure with preserved ejection fraction (HFPEF), and summarizes the evidence and mechanisms by which exercise training can improve symptoms and HF. Clinical and practical aspects of exercise training prescription are also discussed. Libertas Academica 2015-02-09 /pmc/articles/PMC4324467/ /pubmed/25698883 http://dx.doi.org/10.4137/CMC.S21372 Text en © 2015 the author(s), publisher and licensee Libertas Academica Ltd. This is an open access article published under the Creative Commons CC-BY-NC 3.0 license.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Asrar Ul Haq, Muhammad Goh, Cheng Yee Levinger, Itamar Wong, Chiew Hare, David L
spellingShingle	Asrar Ul Haq, Muhammad Goh, Cheng Yee Levinger, Itamar Wong, Chiew Hare, David L Clinical Utility of Exercise Training in Heart Failure with Reduced and Preserved Ejection Fraction
author_facet	Asrar Ul Haq, Muhammad Goh, Cheng Yee Levinger, Itamar Wong, Chiew Hare, David L
author_sort	Asrar Ul Haq, Muhammad
title	Clinical Utility of Exercise Training in Heart Failure with Reduced and Preserved Ejection Fraction
title_short	Clinical Utility of Exercise Training in Heart Failure with Reduced and Preserved Ejection Fraction
title_full	Clinical Utility of Exercise Training in Heart Failure with Reduced and Preserved Ejection Fraction
title_fullStr	Clinical Utility of Exercise Training in Heart Failure with Reduced and Preserved Ejection Fraction
title_full_unstemmed	Clinical Utility of Exercise Training in Heart Failure with Reduced and Preserved Ejection Fraction
title_sort	clinical utility of exercise training in heart failure with reduced and preserved ejection fraction
description	Reduced exercise tolerance is an independent predictor of hospital readmission and mortality in patients with heart failure (HF). Exercise training for HF patients is well established as an adjunct therapy, and there is sufficient evidence to support the favorable role of exercise training programs for HF patients over and above the optimal medical therapy. Some of the documented benefits include improved functional capacity, quality of life (QoL), fatigue, and dyspnea. Major trials to assess exercise training in HF have, however, focused on heart failure with reduced ejection fraction (HFREF). At least half of the patients presenting with HF have heart failure with preserved ejection fraction (HFPEF) and experience similar symptoms of exercise intolerance, dyspnea, and early fatigue, and similar mortality risk and rehospitalization rates. The role of exercise training in the management of HFPEF remains less clear. This article provides a brief overview of pathophysiology of reduced exercise tolerance in HFREF and heart failure with preserved ejection fraction (HFPEF), and summarizes the evidence and mechanisms by which exercise training can improve symptoms and HF. Clinical and practical aspects of exercise training prescription are also discussed.
publisher	Libertas Academica
publishDate	2015
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324467/
_version_	1613186803569786880

Clinical Utility of Exercise Training in Heart Failure with Reduced and Preserved Ejection Fraction

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