Clinical Severity of Visceral Leishmaniasis Is Associated with Changes in Immunoglobulin G Fc N-Glycosylation

Visceral leishmaniasis (VL) has a high fatality rate if not treated; nevertheless, the majority of human infections with the causative agent, Leishmania infantum chagasi, are asymptomatic. Although VL patients often present with increased levels of serum immunoglobulins, the contribution of antibodi...

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Main Authors: Gardinassi, Luiz Gustavo, Dotz, Viktoria, Hipgrave Ederveen, Agnes, de Almeida, Roque Pacheco, Nery Costa, Carlos Henrique, Costa, Dorcas Lamounier, de Jesus, Amélia Ribeiro, Mayboroda, Oleg A., Garcia, Gustavo Rocha, Wuhrer, Manfred, de Miranda Santos, Isabel Kinney Ferreira
Format: Online
Language:English
Published: American Society of Microbiology 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324239/