Down-Regulation of Human Enteric Antimicrobial Peptides by NOD2 during Differentiation of the Paneth Cell Lineage

Down-Regulation of Human Enteric Antimicrobial Peptides by NOD2 during Differentiation of the Paneth Cell Lineage

Ileal Crohn's disease (CD) arising from the alteration of intestinal homeostasis is characterized by two features, namely a decrease in Paneth cell-produced antimicrobial peptides that play a key role in maintaining this balance and an increase in NOD2, an intracellular sensor. Although mutatio...

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Bibliographic Details
Main Authors: Tan, Gao, Li, Run-hua, Li, Chen, Wu, Fang, Zhao, Xin-mei, Ma, Jia-yi, Lei, Shan, Zhang, Wen-di, Zhi, Fa-chao
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323657/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323657/

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