Infective endocarditis in the Lao PDR: Clinical characteristics and outcomes in a developing country

•Data on infective endocarditis (IE) in Southeast Asia are scarce. Most reports on IE originate from tertiary centres in Europe and North America and may not reflect the world's epidemiology of IE.•In Laos, IE remains a disease of young adults with no comorbidities, mainly caused by Streptococc...

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Main Authors: Mirabel, Mariana, Rattanavong, Sayaphet, Frichitthavong, Khamthavy, Chu, Vang, Kesone, Pany, Thongsith, Phonvilay, Jouven, Xavier, Fournier, Pierre-Edouard, Dance, David A.B., Newton, Paul N.
Format: Online
Language:English
Published: Elsevier 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323144/
id pubmed-4323144
recordtype oai_dc
spelling pubmed-43231442015-02-14 Infective endocarditis in the Lao PDR: Clinical characteristics and outcomes in a developing country Mirabel, Mariana Rattanavong, Sayaphet Frichitthavong, Khamthavy Chu, Vang Kesone, Pany Thongsith, Phonvilay Jouven, Xavier Fournier, Pierre-Edouard Dance, David A.B. Newton, Paul N. Article •Data on infective endocarditis (IE) in Southeast Asia are scarce. Most reports on IE originate from tertiary centres in Europe and North America and may not reflect the world's epidemiology of IE.•In Laos, IE remains a disease of young adults with no comorbidities, mainly caused by Streptococcus spp., associated with rheumatic heart disease.•Access to imaging techniques is limited and over half the patients have negative blood cultures.•Cardiac surgery is not routinely used in Laos for acute IE.•Mortality at 2 years follow-up is unacceptably high reaching 39%. Elsevier 2015-02-01 /pmc/articles/PMC4323144/ /pubmed/25482077 http://dx.doi.org/10.1016/j.ijcard.2014.11.184 Text en © 2014 The Authors. Published by Elsevier Ireland Ltd. http://creativecommons.org/licenses/by/3.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/).
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Mirabel, Mariana
Rattanavong, Sayaphet
Frichitthavong, Khamthavy
Chu, Vang
Kesone, Pany
Thongsith, Phonvilay
Jouven, Xavier
Fournier, Pierre-Edouard
Dance, David A.B.
Newton, Paul N.
spellingShingle Mirabel, Mariana
Rattanavong, Sayaphet
Frichitthavong, Khamthavy
Chu, Vang
Kesone, Pany
Thongsith, Phonvilay
Jouven, Xavier
Fournier, Pierre-Edouard
Dance, David A.B.
Newton, Paul N.
Infective endocarditis in the Lao PDR: Clinical characteristics and outcomes in a developing country
author_facet Mirabel, Mariana
Rattanavong, Sayaphet
Frichitthavong, Khamthavy
Chu, Vang
Kesone, Pany
Thongsith, Phonvilay
Jouven, Xavier
Fournier, Pierre-Edouard
Dance, David A.B.
Newton, Paul N.
author_sort Mirabel, Mariana
title Infective endocarditis in the Lao PDR: Clinical characteristics and outcomes in a developing country
title_short Infective endocarditis in the Lao PDR: Clinical characteristics and outcomes in a developing country
title_full Infective endocarditis in the Lao PDR: Clinical characteristics and outcomes in a developing country
title_fullStr Infective endocarditis in the Lao PDR: Clinical characteristics and outcomes in a developing country
title_full_unstemmed Infective endocarditis in the Lao PDR: Clinical characteristics and outcomes in a developing country
title_sort infective endocarditis in the lao pdr: clinical characteristics and outcomes in a developing country
description •Data on infective endocarditis (IE) in Southeast Asia are scarce. Most reports on IE originate from tertiary centres in Europe and North America and may not reflect the world's epidemiology of IE.•In Laos, IE remains a disease of young adults with no comorbidities, mainly caused by Streptococcus spp., associated with rheumatic heart disease.•Access to imaging techniques is limited and over half the patients have negative blood cultures.•Cardiac surgery is not routinely used in Laos for acute IE.•Mortality at 2 years follow-up is unacceptably high reaching 39%.
publisher Elsevier
publishDate 2015
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323144/
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