AUTS2 confers gene activation to Polycomb group proteins in the CNS

Naturally occurring variations of Polycomb Repressive Complex 1 (PRC1) comprise a core assembly of Polycomb group proteins and additional factors that include, surprisingly, Autism Susceptibility Candidate 2 (AUTS2). While AUTS2 is often disrupted in patients with neuronal disorders, the underlying...

Full description

Bibliographic Details
Main Authors: Gao, Zhonghua, Lee, Pedro, Stafford, James M., von Schimmelmann, Melanie, Schaefer, Anne, Reinberg, Danny
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323097/