The novel IκB kinase β inhibitor IMD-0560 prevents bone invasion by oral squamous cell carcinoma

The novel IκB kinase β inhibitor IMD-0560 prevents bone invasion by oral squamous cell carcinoma

Oral squamous cell carcinoma (OSCC) cells display significantly augmented nuclear factor-κB (NF-κB) activity, and inhibiting this activity suppresses malignant tumor characteristics. Thus, we evaluated the effect of IMD-0560, a novel inhibitor of IκB kinase (IKK) β that is under assessment in a clin...

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Bibliographic Details
Main Authors: Tada, Yukiyo, Kokabu, Shoichiro, Sugiyama, Goro, Nakatomi, Chihiro, Aoki, Kazuhiro, Fukushima, Hidefumi, Osawa, Kenji, Sugamori, Yasutaka, Ohya, Keiichi, Okamoto, Masato, Fujikawa, Tomoyuki, Itai, Akiko, Matsuo, Kou, Watanabe, Seiji, Jimi, Eijiro
Format: Online
Language:English
Published: Impact Journals LLC 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322973/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322973/

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