Periodontal Disease and Late-Onset Aortic Prosthetic Vascular Graft Infection
Prosthetic vascular graft infection (PVGI) is a rare but significant complication of arterial reconstructive surgery. Although the relative risk is low, the clinical consequences can be catastrophic. Microbiological data on causative bacteria are limited. We present four cases of late-onset PVGI. Us...
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pubmed-43208052015-02-15 Periodontal Disease and Late-Onset Aortic Prosthetic Vascular Graft Infection Thomas, Stephanie Ghosh, Jonathan Porter, Johnathan Cockcroft, Adele Rautemaa-Richardson, Riina Case Report Prosthetic vascular graft infection (PVGI) is a rare but significant complication of arterial reconstructive surgery. Although the relative risk is low, the clinical consequences can be catastrophic. Microbiological data on causative bacteria are limited. We present four cases of late-onset PVGI. Using a culture-independent nucleic acid amplification method for analysis of intraoperative samples, the presence of bacteria highly suggestive of an oral source was reported. Examination by an oral health specialist confirmed the presence of chronic periodontal disease. We hypothesize that chronic oral infection may be a previously unreported risk factor for the development of late-onset PVGI. Hindawi Publishing Corporation 2015 2015-01-21 /pmc/articles/PMC4320805/ /pubmed/25685592 http://dx.doi.org/10.1155/2015/768935 Text en Copyright © 2015 Stephanie Thomas et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
repository_type |
Open Access Journal |
institution_category |
Foreign Institution |
institution |
US National Center for Biotechnology Information |
building |
NCBI PubMed |
collection |
Online Access |
language |
English |
format |
Online |
author |
Thomas, Stephanie Ghosh, Jonathan Porter, Johnathan Cockcroft, Adele Rautemaa-Richardson, Riina |
spellingShingle |
Thomas, Stephanie Ghosh, Jonathan Porter, Johnathan Cockcroft, Adele Rautemaa-Richardson, Riina Periodontal Disease and Late-Onset Aortic Prosthetic Vascular Graft Infection |
author_facet |
Thomas, Stephanie Ghosh, Jonathan Porter, Johnathan Cockcroft, Adele Rautemaa-Richardson, Riina |
author_sort |
Thomas, Stephanie |
title |
Periodontal Disease and Late-Onset Aortic Prosthetic Vascular Graft Infection |
title_short |
Periodontal Disease and Late-Onset Aortic Prosthetic Vascular Graft Infection |
title_full |
Periodontal Disease and Late-Onset Aortic Prosthetic Vascular Graft Infection |
title_fullStr |
Periodontal Disease and Late-Onset Aortic Prosthetic Vascular Graft Infection |
title_full_unstemmed |
Periodontal Disease and Late-Onset Aortic Prosthetic Vascular Graft Infection |
title_sort |
periodontal disease and late-onset aortic prosthetic vascular graft infection |
description |
Prosthetic vascular graft infection (PVGI) is a rare but significant complication of arterial reconstructive surgery. Although the relative risk is low, the clinical consequences can be catastrophic. Microbiological data on causative bacteria are limited. We present four cases of late-onset PVGI. Using a culture-independent nucleic acid amplification method for analysis of intraoperative samples, the presence of bacteria highly suggestive of an oral source was reported. Examination by an oral health specialist confirmed the presence of chronic periodontal disease. We hypothesize that chronic oral infection may be a previously unreported risk factor for the development of late-onset PVGI. |
publisher |
Hindawi Publishing Corporation |
publishDate |
2015 |
url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320805/ |
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1613185539528196096 |