Periodontal Disease and Late-Onset Aortic Prosthetic Vascular Graft Infection

Prosthetic vascular graft infection (PVGI) is a rare but significant complication of arterial reconstructive surgery. Although the relative risk is low, the clinical consequences can be catastrophic. Microbiological data on causative bacteria are limited. We present four cases of late-onset PVGI. Us...

Full description

Bibliographic Details
Main Authors: Thomas, Stephanie, Ghosh, Jonathan, Porter, Johnathan, Cockcroft, Adele, Rautemaa-Richardson, Riina
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320805/
id pubmed-4320805
recordtype oai_dc
spelling pubmed-43208052015-02-15 Periodontal Disease and Late-Onset Aortic Prosthetic Vascular Graft Infection Thomas, Stephanie Ghosh, Jonathan Porter, Johnathan Cockcroft, Adele Rautemaa-Richardson, Riina Case Report Prosthetic vascular graft infection (PVGI) is a rare but significant complication of arterial reconstructive surgery. Although the relative risk is low, the clinical consequences can be catastrophic. Microbiological data on causative bacteria are limited. We present four cases of late-onset PVGI. Using a culture-independent nucleic acid amplification method for analysis of intraoperative samples, the presence of bacteria highly suggestive of an oral source was reported. Examination by an oral health specialist confirmed the presence of chronic periodontal disease. We hypothesize that chronic oral infection may be a previously unreported risk factor for the development of late-onset PVGI. Hindawi Publishing Corporation 2015 2015-01-21 /pmc/articles/PMC4320805/ /pubmed/25685592 http://dx.doi.org/10.1155/2015/768935 Text en Copyright © 2015 Stephanie Thomas et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Thomas, Stephanie
Ghosh, Jonathan
Porter, Johnathan
Cockcroft, Adele
Rautemaa-Richardson, Riina
spellingShingle Thomas, Stephanie
Ghosh, Jonathan
Porter, Johnathan
Cockcroft, Adele
Rautemaa-Richardson, Riina
Periodontal Disease and Late-Onset Aortic Prosthetic Vascular Graft Infection
author_facet Thomas, Stephanie
Ghosh, Jonathan
Porter, Johnathan
Cockcroft, Adele
Rautemaa-Richardson, Riina
author_sort Thomas, Stephanie
title Periodontal Disease and Late-Onset Aortic Prosthetic Vascular Graft Infection
title_short Periodontal Disease and Late-Onset Aortic Prosthetic Vascular Graft Infection
title_full Periodontal Disease and Late-Onset Aortic Prosthetic Vascular Graft Infection
title_fullStr Periodontal Disease and Late-Onset Aortic Prosthetic Vascular Graft Infection
title_full_unstemmed Periodontal Disease and Late-Onset Aortic Prosthetic Vascular Graft Infection
title_sort periodontal disease and late-onset aortic prosthetic vascular graft infection
description Prosthetic vascular graft infection (PVGI) is a rare but significant complication of arterial reconstructive surgery. Although the relative risk is low, the clinical consequences can be catastrophic. Microbiological data on causative bacteria are limited. We present four cases of late-onset PVGI. Using a culture-independent nucleic acid amplification method for analysis of intraoperative samples, the presence of bacteria highly suggestive of an oral source was reported. Examination by an oral health specialist confirmed the presence of chronic periodontal disease. We hypothesize that chronic oral infection may be a previously unreported risk factor for the development of late-onset PVGI.
publisher Hindawi Publishing Corporation
publishDate 2015
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320805/
_version_ 1613185539528196096