Carbamoyl Radical-Mediated Synthesis and Semipinacol Rearrangement of β-Lactam Diols
In an approach to the biologically important 6-azabicyclo[3.2.1]octane ring system, the scope of the tandem 4-exo-trig carbamoyl radical cyclization—dithiocarbamate group transfer reaction to ring-fused β-lactams is evaluated. β-Lactams fused to five-, six-, and seven-membered rings are prepared in...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
WILEY-VCH Verlag
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320754/ |