The C-Type Lectin Receptor Mincle Binds to Streptococcus pneumoniae but Plays a Limited Role in the Anti-Pneumococcal Innate Immune Response

The innate immune system employs C-type lectin receptors (CLRs) to recognize carbohydrate structures on pathogens and self-antigens. The Macrophage-inducible C-type lectin (Mincle) is a FcRγ-coupled CLR that was shown to bind to mycobacterial cord factor as well as certain fungal species. However, s...

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Bibliographic Details
Main Authors: Rabes, Anne, Zimmermann, Stephanie, Reppe, Katrin, Lang, Roland, Seeberger, Peter H., Suttorp, Norbert, Witzenrath, Martin, Lepenies, Bernd, Opitz, Bastian
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319728/