ABS–Scan: In silico alanine scanning mutagenesis for binding site residues in protein–ligand complex

Most physiological processes in living systems are fundamentally regulated by protein–ligand interactions. Understanding the process of ligand recognition by proteins is a vital activity in molecular biology and biochemistry. It is well known that the residues present at the binding site of the prot...

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Bibliographic Details
Main Authors: Anand, Praveen, Nagarajan, Deepesh, Mukherjee, Sumanta, Chandra, Nagasuma
Format: Online
Language:English
Published: F1000Research 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319546/