Ring closure activates yeast γTuRC for species-specific microtubule nucleation

The γ-tubulin ring complex (γTuRC) is the primary microtubule nucleator in cells. γTuRC is assembled from repeating γ-tubulin small complex (γTuSC) subunits and is thought to function as a template by presenting a γ-tubulin ring that mimics microtubule geometry. However, a previous yeast γTuRC struc...

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Bibliographic Details
Main Authors: Kollman, Justin M., Greenberg, Charles H., Li, Sam, Moritz, Michelle, Zelter, Alex, Fong, Kimberly K., Fernandez, Jose-Jesus, Sali, Andrej, Kilmartin, John, Davis, Trisha N., Agard, David A.
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318760/