Control of repeat protein curvature by computational protein design
Shape complementarity is an important component of molecular recognition, and the ability to precisely adjust the shape of a binding scaffold to match a target of interest would greatly facilitate the creation of high affinity protein reagents and therapeutics. Here we describe a general approach to...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318719/ |