HMGCR is a genetic modifier for risk, age of onset and MCI conversion to Alzheimer’s disease in a three cohorts study
Several retrospective epidemiological studies report that utilization of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) inhibitors called statins at mid-life can reduce the risk of developing sporadic Alzheimer’s disease (AD) by as much as 70%. Conversely, administration of these inhibitors in cli...
Main Authors: | , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318698/ |