Associations of PI3KR1 and mTOR Polymorphisms with Esophageal Squamous Cell Carcinoma Risk and Gene-Environment Interactions in Eastern Chinese Populations

Associations of PI3KR1 and mTOR Polymorphisms with Esophageal Squamous Cell Carcinoma Risk and Gene-Environment Interactions in Eastern Chinese Populations

Single nucleotide polymorphisms (SNPs) in the PI3K/PTEN/AKT/mTOR signaling pathway may contribute to carcinogenesis. We genotyped five potentially functional PIK3R1 and mTOR SNPs in 1116 esophageal squamous cell cancer (ESCC) patients and 1117 cancer-free controls to assess their associations with E...

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Bibliographic Details
Main Authors: Zhu, Jinhong, Wang, Mengyun, Zhu, Meiling, He, Jin, Wang, Jiu-Cun, Jin, Li, Wang, Xiao-Feng, Xiang, Jia-Qing, Wei, Qingyi
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318264/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318264/

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