Short and Efficient Synthesis of Alkyl- and Aryl-Ortho-Hydroxy-Anilides and their Antibiotic Activity

Ortho-hydroxy-anilides are part of natural products like the new antibiotics platencin (A) and platensimycin (B). An important step in the total synthesis of these antibiotics or their derivatives is the preparation of the o-hydroxy-anilide partial structure. The presented method allows the preparat...

Full description

Bibliographic Details
Main Authors: Krauß, Jürgen, Plesch, Eva, Clausen, Sabine, Bracher, Franz
Format: Online
Language:English
Published: Scientia Pharmaceutica 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318158/