Heat shock protein 90 inhibitor NVP-AUY922 exerts potent activity against adult T-cell leukemia–lymphoma cells

Heat shock protein 90 inhibitor NVP-AUY922 exerts potent activity against adult T-cell leukemia–lymphoma cells

Adult T-cell leukemia–lymphoma (ATL), an aggressive neoplasm etiologically associated with HTLV-1, is a chemoresistant malignancy. Heat shock protein 90 (HSP90) is involved in folding and functions as a chaperone for multiple client proteins, many of which are important in tumorigenesis. In this stu...

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Bibliographic Details
Main Authors: Taniguchi, Hiroaki, Hasegawa, Hiroo, Sasaki, Daisuke, Ando, Koji, Sawayama, Yasushi, Imanishi, Daisuke, Taguchi, Jun, Imaizumi, Yoshitaka, Hata, Tomoko, Tsukasaki, Kunihiro, Uno, Naoki, Morinaga, Yoshitomo, Yanagihara, Katsunori, Miyazaki, Yasushi
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317953/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317953/

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