Varenicline enhances dopamine release facilitation more than nicotine after long-term nicotine treatment and withdrawal
An important factor contributing to the high relapse rates among smokers is nicotine withdrawal symptoms. Multiple studies suggest that decreased dopamine release in nucleus accumbens plays a key role in withdrawal. However, recent reports showed that long-term nicotine exposure itself also decrease...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
BlackWell Publishing Ltd
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317236/ |