Severe Staphylococcus lugdunensis keratitis

We report a severe case of Staphylococcus lugdunensis (S. lugdunensis) keratitis presenting as suppurative keratitis in a 77-year-old woman. The patient’s chief complaint was eye pain and decreased visual acuity in her right eye. Suppurative keratitis with a severe corneal abscess was diagnosed by a...

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Main Authors: Inada, N., Harada, N., Nakashima, M., Shoji, J.
Format: Online
Language:English
Published: Springer Berlin Heidelberg 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315482/
id pubmed-4315482
recordtype oai_dc
spelling pubmed-43154822015-02-05 Severe Staphylococcus lugdunensis keratitis Inada, N. Harada, N. Nakashima, M. Shoji, J. Case Report We report a severe case of Staphylococcus lugdunensis (S. lugdunensis) keratitis presenting as suppurative keratitis in a 77-year-old woman. The patient’s chief complaint was eye pain and decreased visual acuity in her right eye. Suppurative keratitis with a severe corneal abscess was diagnosed by a slit-lamp ophthalmic examination. The causative organism was identified as S. lugdunensis by bacterial culture, using a corneal abrasion specimen. She was treated with an intravenous drip infusion of ceftazidime and instillation of gentamicin sulfate ophthalmic solution (six times daily) and ofloxacin ophthalmic ointment (once daily before bedtime) as empiric therapy. Her hospital course was complicated by a corneal perforation of her right eye. The antibiotic susceptibility for S. lugdunensis was sensitive, but with a slightly high MIC for antibiotics used in empiric therapy. The therapeutic drug was changed to levofloxacin ophthalmic solution. The corneal abscess left a scar after healing. Representative causative organisms of suppurative keratitis include Pseudomonas aeruginosa and Streptococcus pneumoniae, but care must be taken in cases involving rare causative organisms. Empiric therapy is necessary for rapidly progressing suppurative keratitis, but a detailed examination of the causative organism is important for therapeutic planning before empiric therapy. Springer Berlin Heidelberg 2014-08-01 2015 /pmc/articles/PMC4315482/ /pubmed/25082203 http://dx.doi.org/10.1007/s15010-014-0669-2 Text en © The Author(s) 2014 Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Inada, N.
Harada, N.
Nakashima, M.
Shoji, J.
spellingShingle Inada, N.
Harada, N.
Nakashima, M.
Shoji, J.
Severe Staphylococcus lugdunensis keratitis
author_facet Inada, N.
Harada, N.
Nakashima, M.
Shoji, J.
author_sort Inada, N.
title Severe Staphylococcus lugdunensis keratitis
title_short Severe Staphylococcus lugdunensis keratitis
title_full Severe Staphylococcus lugdunensis keratitis
title_fullStr Severe Staphylococcus lugdunensis keratitis
title_full_unstemmed Severe Staphylococcus lugdunensis keratitis
title_sort severe staphylococcus lugdunensis keratitis
description We report a severe case of Staphylococcus lugdunensis (S. lugdunensis) keratitis presenting as suppurative keratitis in a 77-year-old woman. The patient’s chief complaint was eye pain and decreased visual acuity in her right eye. Suppurative keratitis with a severe corneal abscess was diagnosed by a slit-lamp ophthalmic examination. The causative organism was identified as S. lugdunensis by bacterial culture, using a corneal abrasion specimen. She was treated with an intravenous drip infusion of ceftazidime and instillation of gentamicin sulfate ophthalmic solution (six times daily) and ofloxacin ophthalmic ointment (once daily before bedtime) as empiric therapy. Her hospital course was complicated by a corneal perforation of her right eye. The antibiotic susceptibility for S. lugdunensis was sensitive, but with a slightly high MIC for antibiotics used in empiric therapy. The therapeutic drug was changed to levofloxacin ophthalmic solution. The corneal abscess left a scar after healing. Representative causative organisms of suppurative keratitis include Pseudomonas aeruginosa and Streptococcus pneumoniae, but care must be taken in cases involving rare causative organisms. Empiric therapy is necessary for rapidly progressing suppurative keratitis, but a detailed examination of the causative organism is important for therapeutic planning before empiric therapy.
publisher Springer Berlin Heidelberg
publishDate 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315482/
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