Nasal Associated Lymphoid Tissue of the Syrian Golden Hamster Expresses High Levels of PrPC

The key event in the pathogenesis of the transmissible spongiform encephalopathies is a template-dependent misfolding event where an infectious isoform of the prion protein (PrPSc) comes into contact with native prion protein (PrPC) and changes its conformation to PrPSc. In many extraneurally inocul...

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Bibliographic Details
Main Authors: Clouse, Melissa D., Shikiya, Ronald A., Bartz, Jason C., Kincaid, Anthony E.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314084/