Coupling of vesicle tethering and Rab binding is required for in vivo functionality of the golgin GMAP-210

Vesicle tethering mediated by the golgin GMAP-210 is required to maintain the structure of the Golgi apparatus. Tethering by GMAP-210 is mediated solely by the ALPS motif, and binding to Rab2 and the length of GMAP-210, although not required for tethering per se, are also critical for its functional...

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Bibliographic Details
Main Authors: Sato, Keisuke, Roboti, Peristera, Mironov, Alexander A., Lowe, Martin
Format: Online
Language:English
Published: The American Society for Cell Biology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310744/