Inferring Active and Prognostic Ligand-Receptor Pairs with Interactions in Survival Regression Models

Modeling signal transduction in cancer cells has implications for targeting new therapies and inferring the mechanisms that improve or threaten a patient’s treatment response. For transcriptome-wide studies, it has been proposed that simple correlation between a ligand and receptor pair implies a re...

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Bibliographic Details
Main Authors: Ruggeri, Christina, Eng, Kevin H
Format: Online
Language:English
Published: Libertas Academica 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310509/