Regulation of Ca2+ transient by PP2A in normal and failing heart
Calcium transient in cardiomyocytes is regulated by multiple protein kinases and phosphatases. PP2A is a major protein phosphatase in the heart modulating Ca2+ handling through an array of ion channels, antiporters and pumps, etc. The assembly, localization/translocation, and substrate specificity o...
Main Authors: | , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Frontiers Media S.A.
2015
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310266/ |