The Mutational Landscape in Pediatric Acute Lymphoblastic Leukemia Deciphered by Whole Genome Sequencing

Genomic characterization of pediatric acute lymphoblastic leukemia (ALL) has identified distinct patterns of genes and pathways altered in patients with well-defined genetic aberrations. To extend the spectrum of known somatic variants in ALL, we performed whole genome and transcriptome sequencing o...

Full description

Bibliographic Details
Main Authors: Lindqvist, Carl Mårten, Nordlund, Jessica, Ekman, Diana, Johansson, Anna, Moghadam, Behrooz Torabi, Raine, Amanda, Övernäs, Elin, Dahlberg, Johan, Wahlberg, Per, Henriksson, Niklas, Abrahamsson, Jonas, Frost, Britt-Marie, Grandér, Dan, Heyman, Mats, Larsson, Rolf, Palle, Josefine, Söderhäll, Stefan, Forestier, Erik, Lönnerholm, Gudmar, Syvänen, Ann-Christine, Berglund, Eva C
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309499/