Molecular Basis for SMC Rod Formation and Its Dissolution upon DNA Binding
SMC condensin complexes are central modulators of chromosome superstructure in all branches of life. Their SMC subunits form a long intramolecular coiled coil, which connects a constitutive “hinge” dimerization domain with an ATP-regulated “head” dimerization module. Here, we address the structural...
Main Authors: | , , , , , , , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Cell Press
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306524/ |