Molecular Basis for SMC Rod Formation and Its Dissolution upon DNA Binding

SMC condensin complexes are central modulators of chromosome superstructure in all branches of life. Their SMC subunits form a long intramolecular coiled coil, which connects a constitutive “hinge” dimerization domain with an ATP-regulated “head” dimerization module. Here, we address the structural...

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Bibliographic Details
Main Authors: Soh, Young-Min, Bürmann, Frank, Shin, Ho-Chul, Oda, Takashi, Jin, Kyeong Sik, Toseland, Christopher P., Kim, Cheolhee, Lee, Hansol, Kim, Soo Jin, Kong, Min-Seok, Durand-Diebold, Marie-Laure, Kim, Yeon-Gil, Kim, Ho Min, Lee, Nam Ki, Sato, Mamoru, Oh, Byung-Ha, Gruber, Stephan
Format: Online
Language:English
Published: Cell Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306524/