A Novel Therapy to Attenuate Acute Kidney Injury and Ischemic Allograft Damage after Allogenic Kidney Transplantation in Mice

Ischemia followed by reperfusion contributes to the initial damage to allografts after kidney transplantation (ktx). In this study we tested the hypothesis that a tetrapeptide EA-230 (AQGV), might improve survival and attenuate loss of kidney function in a mouse model of renal ischemia/reperfusion i...

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Bibliographic Details
Main Authors: Gueler, Faikah, Shushakova, Nelli, Mengel, Michael, Hueper, Katja, Chen, Rongjun, Liu, Xiaokun, Park, Joon-Keun, Haller, Hermann, Wensvoort, Gert, Rong, Song
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305280/