Combining biophysical methods for the analysis of protein complex stoichiometry and affinity in SEDPHAT

Global multi-method analysis for protein interactions (GMMA) can increase the precision and complexity of binding studies for the determination of the stoichiometry, affinity and cooperativity of multi-site interactions. The principles and recent developments of biophysical solution methods implemen...

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Bibliographic Details
Main Authors: Zhao, Huaying, Schuck, Peter
Format: Online
Language:English
Published: International Union of Crystallography 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304681/