Inhibition of Neuronal p38α, but not p38β MAPK, Provides Neuroprotection Against Three Different Neurotoxic Insults
The p38 mitogen-activated protein kinase (MAPK) pathway plays a key role in pathological glial activation and neuroinflammatory responses. Our previous studies demonstrated that microglial p38α and not the p38β isoform is an important contributor to stressor-induced proinflammatory cytokine upregula...
Main Authors: | , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Springer US
2014
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303701/ |