Sensing of Pyrophosphate Metabolites by Vγ9Vδ2 T Cells

The predominant population of γδ T cells in human blood express a T cell receptor (TCR) composed of a Vγ9 (Vγ2 in an alternate nomenclature) and Vδ2 domains. These cells came into the limelight when it was discovered they can respond to certain microbial infections and tumorigenic cells through the...

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Bibliographic Details
Main Authors: Gu, Siyi, Nawrocka, Wioletta, Adams, Erin J.
Format: Online
Language:English
Published: Frontiers Media S.A. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303140/