TP53-induced glycolysis and apoptosis regulator promotes proliferation and invasiveness of nasopharyngeal carcinoma cells

TP53-induced glycolysis and apoptosis regulator promotes proliferation and invasiveness of nasopharyngeal carcinoma cells

The TP53-induced glycolysis and apoptosis regulator (TIGAR) is the protein product of the p53 target gene, C12orf5. TIGAR blocks glycolysis and promotes cellular metabolism via the pentose phosphate pathway; it promotes the production of cellular nicotinamide adenine dinucleotide phosphate (NADPH),...

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Bibliographic Details
Main Authors: WONG, ELAINE YUE LING, WONG, SZE-CHUEN CESAR, CHAN, CHARLES MING LOK, LAM, EMILY KAI YEE, HO, LOUISA YEUNG, LAU, CECILIA PIK YUK, AU, THOMAS CHI CHUEN, CHAN, AMANDA KIT CHING, TSANG, CHI MAN, TSAO, SAI WAH, LUI, VIVIAN WAI YAN, CHAN, ANTHONY TAK CHEUNG
Format: Online
Language:English
Published: D.A. Spandidos 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301475/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301475/

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