Merkel Cell Polyomavirus Small T Antigen Mediates Microtubule Destabilization To Promote Cell Motility and Migration

Merkel cell carcinoma (MCC) is an aggressive skin cancer of neuroendocrine origin with a high propensity for recurrence and metastasis. Merkel cell polyomavirus (MCPyV) causes the majority of MCC cases due to the expression of the MCPyV small and large tumor antigens (ST and LT, respectively). Altho...

Full description

Bibliographic Details
Main Authors: Knight, Laura M., Stakaityte, Gabriele, Wood, Jennifer, J., Abdul-Sada, Hussein, Griffiths, David A., Howell, Gareth J., Wheat, Rachel, Blair, G. Eric, Steven, Neil M., Macdonald, Andrew, Blackbourn, David J., Whitehouse, Adrian
Format: Online
Language:English
Published: American Society for Microbiology 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301106/