Identification of Aptamer-Binding Sites in Hepatitis C Virus Envelope Glycoprotein E2

Hepatitis C Virus (HCV) encodes two envelope glycoproteins, E1 and E2. Our previous work selected a specific aptamer ZE2, which could bind to E2 with high affinity, with a great potential for developing new molecular probes as an early diagnostic reagents or therapeutic drugs targeting HCV. In this...

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Bibliographic Details
Main Authors: Chen, Fan, Chen, Si-Chong, Zhou, Jing, Chen, Zhi-De, Chen, Fang
Format: Online
Language:English
Published: Shiraz University of Medical Sciences 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300483/