Connectivity supporting attention in children with attention deficit hyperactivity disorder

Intra-subject variability (ISV) is the most consistent behavioral deficit in Attention Deficit Hyperactivity Disorder (ADHD). ISV may be associated with networks involved in sustaining task control (cingulo-opercular network: CON) and self-reflective lapses of attention (default mode network: DMN)....

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Main Authors: Barber, Anita D., Jacobson, Lisa A., Wexler, Joanna L., Nebel, Mary Beth, Caffo, Brian S., Pekar, James J., Mostofsky, Stewart H.
Format: Online
Language:English
Published: Elsevier 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299959/
id pubmed-4299959
recordtype oai_dc
spelling pubmed-42999592015-01-21 Connectivity supporting attention in children with attention deficit hyperactivity disorder Barber, Anita D. Jacobson, Lisa A. Wexler, Joanna L. Nebel, Mary Beth Caffo, Brian S. Pekar, James J. Mostofsky, Stewart H. Regular Article Intra-subject variability (ISV) is the most consistent behavioral deficit in Attention Deficit Hyperactivity Disorder (ADHD). ISV may be associated with networks involved in sustaining task control (cingulo-opercular network: CON) and self-reflective lapses of attention (default mode network: DMN). The current study examined whether connectivity supporting attentional control is atypical in children with ADHD. Group differences in full-brain connection strength and brain–behavior associations with attentional control measures were examined for the late-developing CON and DMN in 50 children with ADHD and 50 typically-developing (TD) controls (ages 8–12 years). Elsevier 2014-11-20 /pmc/articles/PMC4299959/ /pubmed/25610768 http://dx.doi.org/10.1016/j.nicl.2014.11.011 Text en © 2014 The Authors http://creativecommons.org/licenses/by-nc-sa/3.0/ This is an open access article under the CC BY-NC-SA license (http://creativecommons.org/licenses/by-nc-sa/3.0/).
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Barber, Anita D.
Jacobson, Lisa A.
Wexler, Joanna L.
Nebel, Mary Beth
Caffo, Brian S.
Pekar, James J.
Mostofsky, Stewart H.
spellingShingle Barber, Anita D.
Jacobson, Lisa A.
Wexler, Joanna L.
Nebel, Mary Beth
Caffo, Brian S.
Pekar, James J.
Mostofsky, Stewart H.
Connectivity supporting attention in children with attention deficit hyperactivity disorder
author_facet Barber, Anita D.
Jacobson, Lisa A.
Wexler, Joanna L.
Nebel, Mary Beth
Caffo, Brian S.
Pekar, James J.
Mostofsky, Stewart H.
author_sort Barber, Anita D.
title Connectivity supporting attention in children with attention deficit hyperactivity disorder
title_short Connectivity supporting attention in children with attention deficit hyperactivity disorder
title_full Connectivity supporting attention in children with attention deficit hyperactivity disorder
title_fullStr Connectivity supporting attention in children with attention deficit hyperactivity disorder
title_full_unstemmed Connectivity supporting attention in children with attention deficit hyperactivity disorder
title_sort connectivity supporting attention in children with attention deficit hyperactivity disorder
description Intra-subject variability (ISV) is the most consistent behavioral deficit in Attention Deficit Hyperactivity Disorder (ADHD). ISV may be associated with networks involved in sustaining task control (cingulo-opercular network: CON) and self-reflective lapses of attention (default mode network: DMN). The current study examined whether connectivity supporting attentional control is atypical in children with ADHD. Group differences in full-brain connection strength and brain–behavior associations with attentional control measures were examined for the late-developing CON and DMN in 50 children with ADHD and 50 typically-developing (TD) controls (ages 8–12 years).
publisher Elsevier
publishDate 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299959/
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