Greater Intermanual Transfer in the Elderly Suggests Age-Related Bilateral Motor Cortex Activation Is Compensatory

ABSTRACT. Hemispheric lateralization of movement control diminishes with age; whether this is compensatory or maladaptive is debated. The authors hypothesized that if compensatory, bilateral activation would lead to greater intermanual transfer in older subjects learning tasks that activate the cor...

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Main Authors:	Graziadio, Sara, Nazarpour, Kianoush, Gretenkord, Sabine, Jackson, Andrew, Eyre, Janet A.
Format:	Online
Language:	English
Published:	Routledge 2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299868/

id	pubmed-4299868
recordtype	oai_dc
spelling	pubmed-42998682015-01-26 Greater Intermanual Transfer in the Elderly Suggests Age-Related Bilateral Motor Cortex Activation Is Compensatory Graziadio, Sara Nazarpour, Kianoush Gretenkord, Sabine Jackson, Andrew Eyre, Janet A. Research Article ABSTRACT. Hemispheric lateralization of movement control diminishes with age; whether this is compensatory or maladaptive is debated. The authors hypothesized that if compensatory, bilateral activation would lead to greater intermanual transfer in older subjects learning tasks that activate the cortex unilaterally in young adults. They studied 10 young and 14 older subjects, learning a unimanual visuomotor task comprising a feedforward phase, where there is unilateral cortical activation in young adults, and a feedback phase, which activates the cortex bilaterally in both age groups. Increased intermanual transfer was demonstrated in older subjects during feedforward learning, with no difference between groups during feedback learning. This finding is consistent with bilateral cortical activation being compensatory to maintain performance despite declining computational efficiency in neural networks. Routledge 2015-01-02 2015-01-09 /pmc/articles/PMC4299868/ /pubmed/25575222 http://dx.doi.org/10.1080/00222895.2014.981501 Text en © 2015 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Graziadio, Sara Nazarpour, Kianoush Gretenkord, Sabine Jackson, Andrew Eyre, Janet A.
spellingShingle	Graziadio, Sara Nazarpour, Kianoush Gretenkord, Sabine Jackson, Andrew Eyre, Janet A. Greater Intermanual Transfer in the Elderly Suggests Age-Related Bilateral Motor Cortex Activation Is Compensatory
author_facet	Graziadio, Sara Nazarpour, Kianoush Gretenkord, Sabine Jackson, Andrew Eyre, Janet A.
author_sort	Graziadio, Sara
title	Greater Intermanual Transfer in the Elderly Suggests Age-Related Bilateral Motor Cortex Activation Is Compensatory
title_short	Greater Intermanual Transfer in the Elderly Suggests Age-Related Bilateral Motor Cortex Activation Is Compensatory
title_full	Greater Intermanual Transfer in the Elderly Suggests Age-Related Bilateral Motor Cortex Activation Is Compensatory
title_fullStr	Greater Intermanual Transfer in the Elderly Suggests Age-Related Bilateral Motor Cortex Activation Is Compensatory
title_full_unstemmed	Greater Intermanual Transfer in the Elderly Suggests Age-Related Bilateral Motor Cortex Activation Is Compensatory
title_sort	greater intermanual transfer in the elderly suggests age-related bilateral motor cortex activation is compensatory
description	ABSTRACT. Hemispheric lateralization of movement control diminishes with age; whether this is compensatory or maladaptive is debated. The authors hypothesized that if compensatory, bilateral activation would lead to greater intermanual transfer in older subjects learning tasks that activate the cortex unilaterally in young adults. They studied 10 young and 14 older subjects, learning a unimanual visuomotor task comprising a feedforward phase, where there is unilateral cortical activation in young adults, and a feedback phase, which activates the cortex bilaterally in both age groups. Increased intermanual transfer was demonstrated in older subjects during feedforward learning, with no difference between groups during feedback learning. This finding is consistent with bilateral cortical activation being compensatory to maintain performance despite declining computational efficiency in neural networks.
publisher	Routledge
publishDate	2015
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299868/
_version_	1613178463455281152

Greater Intermanual Transfer in the Elderly Suggests Age-Related Bilateral Motor Cortex Activation Is Compensatory

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