Impact of Viral Activators and Epigenetic Regulators on HIV-1 LTRs Containing Naturally Occurring Single Nucleotide Polymorphisms
Following human immunodeficiency virus type 1 (HIV-1) integration into host cell DNA, the viral promoter can become transcriptionally silent in the absence of appropriate signals and factors. HIV-1 gene expression is dependent on regulatory elements contained within the long terminal repeat (LTR) th...
Main Authors: | Shah, Sonia, Pirrone, Vanessa, Alexaki, Aikaterini, Nonnemacher, Michael R., Wigdahl, Brian |
---|---|
Format: | Online |
Language: | English |
Published: |
Hindawi Publishing Corporation
2015
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299542/ |
Similar Items
-
Functional properties of the HIV-1 long terminal repeat containing single-nucleotide polymorphisms in Sp site III and CCAAT/enhancer binding protein site I
by: Shah, Sonia, et al.
Published: (2014) -
Effect of μ-opioid agonist DAMGO on surface CXCR4 and HIV-1 replication in TF-1 human bone marrow progenitor cells
by: Strazza, Marianne, et al.
Published: (2014) -
Epigenetic modifications of HIV proviral LTRs: potential targets for cure
by: Doerfler, W, et al.
Published: (2012) -
HIV-1 Promoter Single Nucleotide Polymorphisms Are Associated with Clinical Disease Severity
by: Nonnemacher, Michael R., et al.
Published: (2016) -
Cellular phenotype impacts human immunodeficiency virus type 1 viral protein R subcellular localization
by: Ferrucci, Adriano, et al.
Published: (2011)