Genome-wide gene order distances support clustering the gram-positive bacteria

Initially using 143 genomes, we developed a method for calculating the pair-wise distance between prokaryotic genomes using a Monte Carlo method to estimate the conservation of gene order. The method was based on repeatedly selecting five or six non-adjacent random orthologs from each of two genomes...

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Bibliographic Details
Main Authors: House, Christopher H., Pellegrini, Matteo, Fitz-Gibbon, Sorel T.
Format: Online
Language:English
Published: Frontiers Media S.A. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299520/