Cell-autonomous signal transduction in the Xenopus egg Wnt/β-catenin pathway

Wnt proteins are thought to bind to their receptors on the cell surfaces of neighboring cells. Wnt8 likely substitutes for the dorsal determinants in Xenopus embryos to dorsalize early embryos via the Wnt/β-catenin pathway. Here, we show that Wnt8 can dorsalize Xenopus embryos working cell autonomou...

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Bibliographic Details
Main Authors: Motomura, Eriko, Narita, Tomohiro, Nasu, Yuya, Kato, Hirotaka, Sedohara, Ayako, Nishimatsu, Shin-ichiro, Sakai, Masao
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298249/