Evaluation of de novo transcriptome assemblies from RNA-Seq data

De novo RNA-Seq assembly facilitates the study of transcriptomes for species without sequenced genomes, but it is challenging to select the most accurate assembly in this context. To address this challenge, we developed a model-based score, RSEM-EVAL, for evaluating assemblies when the ground truth...

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Bibliographic Details
Main Authors: Li, Bo, Fillmore, Nathanael, Bai, Yongsheng, Collins, Mike, Thomson, James A, Stewart, Ron, Dewey, Colin N
Format: Online
Language:English
Published: BioMed Central 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298084/