Dynamic expression of T-bet and GATA3 by regulatory T cells maintains immune tolerance

Regulatory T (Treg) cells can express the transcription factors T-bet and GATA3 but the function of this expression and whether such cells represent stable subsets is still unknown. By using multiple reporter tools, we show that the expression of T-bet and GATA3 in Treg cells is dynamically influenc...

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Bibliographic Details
Main Authors: Yu, Fang, Sharma, Suveena, Edwards, Julie, Feigenbaum, Lionel, Zhu, Jinfang
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297509/