The catalytically inactive tyrosine phosphatase HD-PTP/PTPN23 is a novel regulator of SMN complex localization

This first systematic and comprehensive screen of human phosphatases for a regulatory role in the survival motor neuron (SMN) complex identifies the catalytically inactive, non–receptor-type tyrosine phosphatase PTPN23/HD-PTP as a novel SMN complex regulator. PTPN23 maintains a highly phosphorylated...

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Bibliographic Details
Main Authors: Husedzinovic, Alma, Neumann, Beate, Reymann, Jürgen, Draeger-Meurer, Stefanie, Chari, Ashwin, Erfle, Holger, Fischer, Utz, Gruss, Oliver J.
Format: Online
Language:English
Published: The American Society for Cell Biology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294665/