Glial metabotropic glutamate receptor-4 increases maturation and survival of oligodendrocytes

Glial metabotropic glutamate receptor-4 increases maturation and survival of oligodendrocytes

Group III metabotropic glutamate (mGlu) receptors mediate important neuroprotective and anti-inflammatory effects. Stimulation of mGlu4 receptor reduces neuroinflammation in a mouse model of experimental autoimmune encephalomyelitis (EAE) whereas mGlu4 knockout mice display exacerbated EAE clinical...

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Bibliographic Details
Main Authors: Spampinato, Simona Federica, Merlo, Sara, Chisari, Mariangela, Nicoletti, Ferdinando, Sortino, Maria Angela
Format: Online
Language:English
Published: Frontiers Media S.A. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294134/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294134/

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