Biochemical and structural characterization of the apicoplast dihydrolipoamide dehydrogenase of Plasmodium falciparum

PDC (pyruvate dehydrogenase complex) is a multi-enzyme complex comprising an E1 (pyruvate decarboxylase), an E2 (dihydrolipomide acetyltransferase) and an E3 (dihydrolipoamide dehydrogenase). PDC catalyses the decarboxylation of pyruvate and forms acetyl-CoA and NADH. In the human malaria parasite P...

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Bibliographic Details
Main Authors: Laine, Larissa M., Biddau, Marco, Byron, Olwyn, Müller, Sylke
Format: Online
Language:English
Published: Portland Press Ltd. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293902/