Leptin’s metabolic and immune functions can be uncoupled at the ligand/receptor interaction level

The adipocyte-derived cytokine leptin acts as a metabolic switch, connecting the body’s metabolism to high-energy consuming processes such as reproduction and immune responses. We here provide genetic and biochemical evidence that the metabolic and immune functions of leptin can be uncoupled at the...

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Bibliographic Details
Main Authors: Zabeau, Lennart, Jensen, Cathy J., Seeuws, Sylvie, Venken, Koen, Verhee, Annick, Catteeuw, Dominiek, van Loo, Geert, Chen, Hui, Walder, Ken, Hollis, Jacob, Foote, Simon, Morris, Margaret J., Van der Heyden, José, Peelman, Frank, Oldfield, Brian J., Rubio, Justin P., Elewaut, Dirk, Tavernier, Jan
Format: Online
Language:English
Published: Springer Basel 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293488/